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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MYBPC3 All Species: 9.39
Human Site: S139 Identified Species: 22.96
UniProt: Q14896 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14896 NP_000247.2 1273 140606 S139 P S P K G S S S A A L N G P T
Chimpanzee Pan troglodytes XP_508410 1219 134426 S139 P S P K G S S S A A L N G P T
Rhesus Macaque Macaca mulatta XP_001091952 1171 131678 L127 F K G K W M D L A S K A G K H
Dog Lupus familis XP_533608 1141 128021 V120 S A S N V Y T V E L H I G K V
Cat Felis silvestris
Mouse Mus musculus O70468 1270 140614 S134 S S P E G S V S V T Q D G S A
Rat Rattus norvegicus Q63518 621 68718
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506731 1227 137283 S139 Q S L E R K D S E W S L G E G
Chicken Gallus gallus Q90688 1272 142270 A133 Q N P E V P P A E T Q P E E P
Frog Xenopus laevis NP_001082167 1282 144058 S145 E A K P P E S S E A T A T Q P
Zebra Danio Brachydanio rerio NP_001037814 1265 142292 A141 P A P T E N S A P E S T G P P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.9 46.8 51.1 N.A. 88.4 20.5 N.A. 45.9 69.4 64.7 63.2 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 94.4 63.9 65 N.A. 91.9 32.4 N.A. 62.4 82.3 78.7 76.9 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 20 6.6 N.A. 40 0 N.A. 20 6.6 20 33.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 26.6 20 N.A. 53.3 0 N.A. 26.6 26.6 26.6 53.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 30 0 0 0 0 0 20 30 30 0 20 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 20 0 0 0 0 10 0 0 0 % D
% Glu: 10 0 0 30 10 10 0 0 40 10 0 0 10 20 0 % E
% Phe: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 10 0 30 0 0 0 0 0 0 0 70 0 10 % G
% His: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 10 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % I
% Lys: 0 10 10 30 0 10 0 0 0 0 10 0 0 20 0 % K
% Leu: 0 0 10 0 0 0 0 10 0 10 20 10 0 0 0 % L
% Met: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 10 0 10 0 10 0 0 0 0 0 20 0 0 0 % N
% Pro: 30 0 50 10 10 10 10 0 10 0 0 10 0 30 30 % P
% Gln: 20 0 0 0 0 0 0 0 0 0 20 0 0 10 0 % Q
% Arg: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 20 40 10 0 0 30 40 50 0 10 20 0 0 10 0 % S
% Thr: 0 0 0 10 0 0 10 0 0 20 10 10 10 0 20 % T
% Val: 0 0 0 0 20 0 10 10 10 0 0 0 0 0 10 % V
% Trp: 0 0 0 0 10 0 0 0 0 10 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _